Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.58 |
| ▸ | PLG | P00747 | 9/20 | 0.55 |
| ▸ | PROC | P04070 | 2/20 | 0.55 |
| ▸ | F2 | P00734 | 4/20 | 0.49 |
| ▸ | PLAU | P00749 | 3/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | F12 | P00748 | 1/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7999717 | 0.92 | F10 (0.57) | F10PLGPROCF2 | |
| SCHEMBL7999864 | 0.90 | F10 (0.59) | F10PLGPROCF2PRSS1 | |
| SCHEMBL7996279 | 0.90 | F10 (0.46) | F10PLGPROCF2PRSS1 | |
| SCHEMBL7997631 | 0.87 | F10 (0.63) | F10PLGPROCF2PRSS1 | |
| SCHEMBL7999868 | 0.80 | F10 (0.74) | F10PLGPROCF2 | |
| Hydrochloric Acid SCHEMBL6895363 | 0.79 | F10 (0.73) | F10PLGPROCF2 | |
| SCHEMBL7996139 | 0.79 | F10 (0.54) | F10PLGPROCF2 | |
| SCHEMBL7997641 | 0.79 | F10 (0.58) | F10PLGPROCF2PRSS1 | |
| SCHEMBL7986939 | 0.78 | F10 (0.66) | F10PLGPROCF2PRSS1 | |
| SCHEMBL1651311 | 0.78 | F10 (0.65) | F10PLGPROCF2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000008005-A2 | PIPERAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-02-17 | — | — | WO | claimed |
| WO-2000008005-A2 | PIPERAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-02-17 | — | — | WO | disclosed |