Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.59 |
| ▸ | F2 | P00734 | 14/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.59 |
| ▸ | PLG | P00747 | 1/20 | 0.59 |
| ▸ | PROC | P04070 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997641 | 0.90 | F10 (0.58) | F10F2PRSS1PLGPROC | |
| SCHEMBL7996275 | 0.90 | F10 (0.58) | F10F2PRSS1PLGPROC | |
| SCHEMBL7986939 | 0.89 | F10 (0.66) | F10F2PRSS1PLGPROC | |
| SCHEMBL1651311 | 0.87 | F10 (0.65) | F10F2PRSS1PLGPROC | |
| SCHEMBL7999717 | 0.86 | F10 (0.57) | F10F2PLGPROC | |
| SCHEMBL8003260 | 0.81 | F10 (0.58) | F10F2PRSS1PLGPROC | |
| SCHEMBL7996279 | 0.80 | F10 (0.46) | F10F2PRSS1PLGPROC | |
| SCHEMBL8003154 | 0.79 | HCRTR1 (0.47) | — | |
| SCHEMBL7999856 | 0.79 | F10 (0.64) | F10F2PRSS1PLGPROC | |
| SCHEMBL7997631 | 0.78 | F10 (0.63) | F10F2PRSS1PLGPROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000008005-A2 | PIPERAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-02-17 | — | — | WO | disclosed |