Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 6/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.38 |
| ▸ | BID | P55957 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | IAPP | P10997 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996173 | 1.00 | MGLL (0.46) | MGLLMPOSLC6A4TAAR1HTR1A | |
| SCHEMBL7984588 | 1.00 | MGLL (0.46) | MGLLMPOSLC6A4TAAR1HTR1A | |
| SCHEMBL6535029 | 0.98 | MGLL (0.44) | MGLLMPOSLC6A4TAAR1HTR1A | |
| SCHEMBL6534990 | 0.93 | MPO (0.45) | MGLLMPOSLC6A4TAAR1HTR1A | |
| SCHEMBL6535097 | 0.86 | TAAR1 (0.47) | MGLLMPOSLC6A4TAAR1HTR1A | |
| SCHEMBL7984558 | 0.80 | MPO (0.45) | MGLLMPOSLC6A4TAAR1HTR1A | |
| SCHEMBL7984424 | 0.79 | MGLL (0.44) | MGLLMPOSLC6A4TAAR1HTR1A | |
| SCHEMBL8402231 | 0.78 | MGLL (0.66) | MGLLMPOSLC6A4TAAR1HTR1A | |
| SCHEMBL8398317 | 0.78 | MGLL (0.66) | MGLLMPOSLC6A4TAAR1HTR1A | |
| SCHEMBL8400524 | 0.78 | MGLL (0.66) | MGLLMPOSLC6A4TAAR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284918-B1 | ENZYME INHIBITORS | VANDERBILT UNIVERSITY | 2001-09-04 | — | — | US | disclosed |