Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TEK | Q02763 | 2/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | BCHE | P06276 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8008240 | 0.92 | KDM4E (0.63) | KDM4EALDH1A1GAATSHRLMNA | |
| SCHEMBL27207545 | 0.90 | BCHE (0.58) | KDM4EALDH1A1GAATSHRLMNA | |
| SCHEMBL27241995 | 0.90 | BCHE (0.58) | KDM4EALDH1A1GAATSHRLMNA | |
| SCHEMBL7995686 | 0.85 | TEK (0.58) | KDM4EALDH1A1GAATSHRLMNA | |
| SCHEMBL10808273 | 0.84 | BCHE (0.43) | KDM4EALDH1A1GAATSHRLMNA | |
| SCHEMBL27199775 | 0.84 | LMNA (0.49) | KDM4EALDH1A1GAATSHRLMNA | |
| SCHEMBL8797108 | 0.83 | DRD2 (0.49) | KDM4EALDH1A1GAATSHRLMNA | |
| SCHEMBL8011827 | 0.83 | KDM4E (0.44) | KDM4EALDH1A1GAATSHRLMNA | |
| SCHEMBL18152846 | 0.82 | TSHR (0.61) | KDM4EALDH1A1TSHRPDE4BHSD17B10 | |
| SCHEMBL27237036 | 0.81 | BCHE (0.53) | KDM4EALDH1A1GAATSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000019994-A9 | ESTROGEN RECEPTOR LIGANDS | UNIV ILLINOIS (US) | 2000-08-31 | — | — | WO | disclosed |
| WO-2000019994-A1 | ESTROGEN RECEPTOR LIGANDS | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2000-04-13 | — | — | WO | disclosed |