SCHEMBL799649

SCHEMBL799649

COc1cc(O)cc2c1C(=O)C[C@@H](c1ccc(O)cc1)O2

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS2R31 P59538 2/20 0.72
CYP19A1 P11511 5/20 0.70
CYP3A4 P08684 5/20 0.70
CYP1A1 P04798 4/20 0.70
CYP1A2 P05177 4/20 0.70
CYP1B1 Q16678 4/20 0.70
HSD17B10 Q99714 3/20 0.70
TDP1 Q9NUW8 2/20 0.70
CA12 O43570 2/20 0.70
CYP2C9 P11712 2/20 0.70
CA4 P22748 2/20 0.70
DPP4 P27487 2/20 0.70
CYP2C19 P33261 2/20 0.70
CA7 P43166 2/20 0.70
GSK3B P49841 2/20 0.70
MEN1 O00255 2/20 0.70
KMT2A Q03164 2/20 0.70
ALOX12 P18054 1/20 0.70
SLCO2B1 O94956 1/20 0.70
TTR P02766 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30641776 1.00 TAS2R31 (0.72) TAS2R31CYP19A1CYP3A4CYP1A1CYP1A2
SCHEMBL773766 1.00 TAS2R31 (0.72) TAS2R31CYP19A1CYP3A4CYP1A1CYP1A2
Alpinetin SCHEMBL30741428 0.93 CYP1A1 (0.80) TAS2R31CYP19A1CYP3A4CYP1A1CYP1A2
Alpinetin SCHEMBL29844118 0.93 CYP1A1 (0.80) TAS2R31CYP19A1CYP3A4CYP1A1CYP1A2
Alpinetin SCHEMBL29580312 0.93 CYP1A1 (0.80) TAS2R31CYP19A1CYP3A4CYP1A1CYP1A2
SCHEMBL26118588 0.91 CYP3A4 (0.65) TAS2R31CYP19A1CYP3A4CYP1A1CYP1A2
SCHEMBL1460821 0.91 HSD17B10 (0.76) TAS2R31CYP19A1CYP3A4CYP1A1CYP1A2
SCHEMBL11128429 0.91 HSD17B10 (0.76) TAS2R31CYP19A1CYP3A4CYP1A1CYP1A2
SCHEMBL1460823 0.91 HSD17B10 (0.76) TAS2R31CYP19A1CYP3A4CYP1A1CYP1A2
SCHEMBL29722583 0.91 HSD17B10 (0.76) TAS2R31CYP19A1CYP3A4CYP1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120005740-A Recombinant microorganism for high-level synthesis of polyphenol compounds and application thereof 中国科学院天津工业生物技术研究所 2025-05-16 CN claimed
CN-120005740-A Recombinant microorganism for high-level synthesis of polyphenol compounds and application thereof 中国科学院天津工业生物技术研究所 2025-05-16 CN disclosed
US-8431166-B2 Composition comprising the extract of Anemarrhena asphodeloides Bunge or the compounds isolated from the same for preventing and treating lipid metabolism disorder EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION (KR) 2013-04-30 US disclosed
US-8431166-B2 Composition comprising the extract of Anemarrhena asphodeloides Bunge or the compounds isolated from the same for preventing and treating lipid metabolism disorder EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION (KR) 2013-04-30 US disclosed
US-20120070515-A1 Composition Comprising the Extract of Anemarrhena Asphodeloides Bunge or the Compounds Isolated from the Same for Preventing and Treating Lipid Metabolism Disorder EWHA UNIVERSITY- INDUSTRY COLLABORATION FOUNDATION (KR) 2012-03-22 US disclosed
US-20120070515-A1 Composition Comprising the Extract of Anemarrhena Asphodeloides Bunge or the Compounds Isolated from the Same for Preventing and Treating Lipid Metabolism Disorder EWHA UNIVERSITY- INDUSTRY COLLABORATION FOUNDATION (KR) 2012-03-22 US disclosed
WO-2010120029-A1 COMPOSITION COMPRISING THE EXTRACT OF ANEMARRHENA ASPHODELOIDES BUNGE OR THE COMPOUNDS ISOLATED FROM THE SAME FOR PREVENTING AND TREATING LIPID METABOLISM DISORDER EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) 2010-10-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120070515-A1 Composition Comprising the Extract of Anemarrhena Asphodeloides Bunge or the Compounds Isolated from the Same for Preventing and Treating Lipid Metabolism Disorder FABP4, ACACB, LIPC TAS2R31 3954/4885CYP19A1 119/4885CYP3A4 1261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.