Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 13/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 3/20 | 0.42 |
| ▸ | PGK1 | P00558 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996741 | 0.79 | KDR (0.49) | KDRHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL1465529 | 0.78 | KDR (0.46) | KDRHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL6542710 | 0.73 | KDR (0.62) | KDRALDH1A1 | |
| SCHEMBL427330 | 0.70 | KDR (0.69) | KDRFLT1 | |
| SCHEMBL8002375 | 0.69 | KMT2A (0.48) | HDAC3HDAC1HDAC2HDAC6SMN1; SMN2 | |
| SCHEMBL1466583 | 0.69 | KDR (0.60) | KDRHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL1715372 | 0.68 | KDR (0.65) | KDR | |
| SCHEMBL28236466 | 0.68 | KDR (0.62) | KDR | |
| SCHEMBL2636627 | 0.68 | KDM4E (0.34) | SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL24693282 | 0.67 | KDR (0.52) | KDRHDAC3HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001085715-A2 | AZA- AND POLYAZANTHRANYL AMIDES AND THEIR USE AS MEDICAMENTS | NOVARTIS AG (CH) | 2001-11-15 | — | — | WO | claimed |
| WO-2001085715-A2 | AZA- AND POLYAZANTHRANYL AMIDES AND THEIR USE AS MEDICAMENTS | NOVARTIS AG (CH) | 2001-11-15 | — | — | WO | disclosed |