Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28007567 | 0.79 | LMNA (0.34) | KDM4EHPGDHSD17B10ALDH1A1MAPT | |
| SCHEMBL6186076 | 0.78 | HSD17B10 (0.33) | KDM4EHPGDHSD17B10ALDH1A1MAPT | |
| SCHEMBL7994968 | 0.78 | ATR (0.34) | KDM4EHPGDHSD17B10ALDH1A1MAPT | |
| SCHEMBL4632562 | 0.78 | PRKCI (0.38) | KDM4EHPGDHSD17B10ALDH1A1MAPT | |
| SCHEMBL7534857 | 0.77 | NAPRT (0.34) | KDM4E | |
| SCHEMBL6639870 | 0.72 | KDM4E (0.50) | KDM4EHPGDHSD17B10ALDH1A1MAPT | |
| SCHEMBL8378283 | 0.71 | KDM4E (0.45) | KDM4EHPGDHSD17B10ALDH1A1MAPT | |
| SCHEMBL4634043 | 0.71 | TDP1 (0.42) | KDM4EHPGDHSD17B10ALDH1A1ALOX15 | |
| SCHEMBL8559884 | 0.69 | PTPN11 (0.36) | KDM4EHPGDHSD17B10ALDH1A1TDP1 | |
| SCHEMBL2636206 | 0.68 | HTT (0.49) | HPGDALDH1A1MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2438071-A1 | SUBSTITUTED PYRAZINE (THIO)PYRANS WITH A HERBICIDAL ACTION | BASF SE (DE) | 2012-04-11 | — | — | EP | disclosed |
| WO-2010139657-A1 | SUBSTITUTED PYRAZINE (THIO)PYRANS WITH A HERBICIDAL ACTION | BASF SE (DE) | 2010-12-09 | — | — | WO | disclosed |