Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMBR | P28336 | 6/20 | 0.53 |
| ▸ | MMP2 | P08253 | 3/20 | 0.52 |
| ▸ | MMP8 | P22894 | 3/20 | 0.52 |
| ▸ | MMP9 | P14780 | 2/20 | 0.52 |
| ▸ | BRS3 | P32247 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8003758 | 0.96 | NMBR (0.57) | NMBRMMP2MMP8MMP9BRS3 | |
| SCHEMBL8003779 | 0.93 | NMBR (0.54) | NMBRMMP2MMP8MMP9BRS3 | |
| SCHEMBL7997681 | 0.93 | NMBR (0.54) | NMBRMMP2MMP8MMP9BRS3 | |
| SCHEMBL8007001 | 0.93 | NMBR (0.61) | NMBRMMP2MMP8MMP9BRS3 | |
| SCHEMBL7998272 | 0.91 | MMP2 (0.56) | NMBRMMP2MMP8MMP9BRS3 | |
| SCHEMBL7995483 | 0.91 | NMBR (0.55) | NMBRMMP2MMP8MMP9BRS3 | |
| SCHEMBL7999691 | 0.90 | NMBR (0.51) | NMBRMMP2MMP8MMP9BRS3 | |
| SCHEMBL7999755 | 0.89 | MMP8 (0.65) | MMP2MMP8MMP9MMP1 | |
| SCHEMBL7991571 | 0.88 | NMBR (0.54) | NMBRMMP2MMP8MMP9BRS3 | |
| SCHEMBL7996645 | 0.86 | NMBR (0.55) | NMBRMMP2MMP8MMP9BRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009113320-A1 | MMP INHIBITOR | 株式会社ヤクルト本社 (JP) | 2009-09-17 | — | — | WO | disclosed |