Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8008715 | 0.84 | TDP1 (0.49) | CYP46A1HSD17B10ALDH1A1MAPTMAPK1 | |
| SCHEMBL2186358 | 0.83 | GRM2 (0.40) | EGFRCYP46A1ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL8005894 | 0.83 | SLC7A5 (0.43) | EGFRCYP46A1HSD17B10ALDH1A1MAPT | |
| SCHEMBL7947388 | 0.81 | P2RX3 (0.43) | ATM | |
| SCHEMBL7997686 | 0.79 | KDM4E (0.46) | CYP46A1HSD17B10ALDH1A1MAPTMAPK1 | |
| SCHEMBL3660558 | 0.79 | TDP1 (0.44) | CYP46A1HSD17B10ALDH1A1MAPTMAPK1 | |
| SCHEMBL7996748 | 0.79 | CA12 (0.51) | EGFRCYP46A1HSD17B10ALDH1A1MAPT | |
| SCHEMBL8005875 | 0.79 | TDP1 (0.44) | EGFRCYP46A1HSD17B10ALDH1A1MAPT | |
| SCHEMBL17707305 | 0.78 | TDP1 (0.58) | EGFRCYP46A1HSD17B10ALDH1A1MAPT | |
| SCHEMBL7945903 | 0.78 | NOTUM (0.43) | CYP46A1HSD17B10ALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010033168-A2 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | RENOVIS, INC. (US) | 2010-03-25 | — | — | WO | disclosed |