Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6758482 | 0.69 | — | — | |
| SCHEMBL17313238 | 0.68 | — | — | |
| SCHEMBL30149951 | 0.66 | — | — | |
| SCHEMBL615573 | 0.63 | MEN1 (0.31) | — | |
| SCHEMBL2952 | 0.61 | MEN1 (0.47) | — | |
| SCHEMBL375015 | 0.61 | MEN1 (0.47) | — | |
| Water SCHEMBL28189365 | 0.61 | MEN1 (0.47) | — | |
| SCHEMBL1387747 | 0.61 | CES2 (0.44) | — | |
| SCHEMBL12500062 | 0.61 | MEN1 (0.39) | — | |
| SCHEMBL21443828 | 0.60 | S100A4 (0.43) | S100A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284789-B1 | TETRAHYDRONAPHTHALENE DERIVATIVES OF ALPHA-CONINDENDRIN, BETA-CONINDENDRIN, SIKKIMOTOXIN, AND PODOPHYLLOTOXIN HAVING AT LEAST ONE METHYLENEOXY BRIDGE WHEREIN THE OXYGEN ATOM EXTENDS TO THE BENZHYDRYLIC CARBON ATOM; ANTICANCER AGENTS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2001-09-04 | — | — | US | disclosed |