Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 2/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30610263 | 0.82 | TRPM8 (0.39) | LRRK2ALDH1A1SMN1; SMN2TRPM8LMNA | |
| SCHEMBL15360304 | 0.77 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1SMN1; SMN2LMNANPC1 | |
| SCHEMBL12411096 | 0.72 | ALDH1A1 (0.48) | LRRK2ALDH1A1L3MBTL1MAPTKMT2A | |
| SCHEMBL31330456 | 0.71 | LRRK2 (0.46) | LRRK2SLC29A1PDE10ASMN1; SMN2TRPM8 | |
| SCHEMBL10072452 | 0.70 | LRRK2 (0.44) | LRRK2L3MBTL1SLC29A1PDE10ASMN1; SMN2 | |
| SCHEMBL5903240 | 0.69 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1SMN1; SMN2NPC1TP53 | |
| SCHEMBL2049511 | 0.68 | LRRK2 (0.40) | LRRK2ALDH1A1L3MBTL1PDE10ASMN1; SMN2 | |
| SCHEMBL21394022 | 0.68 | LRRK2 (0.40) | LRRK2L3MBTL1SMN1; SMN2TRPM8LMNA | |
| SCHEMBL7996780 | 0.65 | MAPK1 (0.42) | LRRK2 | |
| SCHEMBL30610259 | 0.65 | MAPK1 (0.42) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143156-A2 | IMIDAZO[1,2-a]PYRIDINE COMPOUNDS | SEPRACOR INC. (US) | 2009-11-26 | — | — | WO | disclosed |