SCHEMBL7996884

SCHEMBL7996884

Cc1ccc(C2=Cc3ccccc3C2[Ti])c2ccccc12

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.42
KDM4E B2RXH2 1/20 0.35
MAPT P10636 1/20 0.35
PABPC1 P11940 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CYP2A6 P11509 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7252931 0.82 CYP1A2 (0.43) CYP1A2KDM4EMAPTPABPC1SMN1; SMN2
SCHEMBL7645586 0.79 CYP1A2 (0.41) CYP1A2KDM4EMAPTPABPC1SMN1; SMN2
Hydrochloric Acid SCHEMBL6898339 0.79 CYP1A2 (0.41) CYP1A2KDM4EMAPTPABPC1SMN1; SMN2
Hydrochloric Acid SCHEMBL21980376 0.77 CYP1A2 (0.35) CYP1A2
SCHEMBL2233259 0.75 CYP1A2 (0.36) CYP1A2
SCHEMBL27618424 0.73 EDNRB (0.33) MAPTSMN1; SMN2
Hydrochloric Acid SCHEMBL6435334 0.70 CYP1A2 (0.32) CYP1A2
SCHEMBL4094216 0.69 LMNA (0.32) SMN1; SMN2
Hydrochloric Acid SCHEMBL8614076 0.68 CYP19A1 (0.31)
Hydrochloric Acid SCHEMBL7638798 0.67 LMNA (0.31) KDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0883623-A4 PREPARATION OF CHIRAL TITANOCENES BOULDER SCIENT CO (US) 2000-06-28 EP disclosed
EP-0883623-A1 PREPARATION OF CHIRAL TITANOCENES BOULDER SCIENTIFIC COMPANY (US) 1998-12-16 EP disclosed
WO-1998022477-A1 PREPARATION OF CHIRAL TITANOCENES BOULDER SCIENTIFIC COMPANY (US) 1998-05-28 WO disclosed