Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4457701 | 0.85 | GAA (0.31) | GAAHPGDMAPK1 | |
| SCHEMBL17583481 | 0.78 | HSD11B1 (0.33) | — | |
| SCHEMBL727342 | 0.74 | GAA (0.33) | GAAHPGDMAPK1 | |
| SCHEMBL206199 | 0.74 | TSHR (0.34) | GAAHPGDMAPK1 | |
| SCHEMBL10907998 | 0.72 | HTT (0.41) | GAAHPGDMAPK1POLB | |
| SCHEMBL13805696 | 0.70 | — | — | |
| SCHEMBL7386336 | 0.69 | KDM1A (0.36) | GAA | |
| SCHEMBL481258 | 0.67 | THRB (0.33) | POLB | |
| SCHEMBL6901500 | 0.65 | HSD11B1 (0.31) | — | |
| SCHEMBL2011171 | 0.65 | HSD11B1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184185-B1 | CYCLIC CARBOXYLIC ACID IMIDE HAVING BORON IN THE MOLECULE AND SUBSTITUTED BY AN ALKYL OR ALKENYL GROUP, WHEREIN THE CYCLIC CARBOXYLIC ACID IMIDE IS CONTAINED AT 0.1 TO 12 WT % BASED ON THE WHOLE COMPOSITION | TONEN CORPORATION (JP) | 2001-02-06 | — | — | US | disclosed |