SCHEMBL7997205

SCHEMBL7997205

C=COB(OC=C)c1cccc([N+](=O)[O-])c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
LMNA P02545 1/20 0.50
GAA P10253 1/20 0.45
HTT P42858 1/20 0.45
KMT2A Q03164 1/20 0.45
ALDH1A1 P00352 3/20 0.43
ACHE P22303 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ALOX15 P16050 1/20 0.43
NFE2L2 Q16236 2/20 0.42
CA2 P00918 2/20 0.42
CA5A P35218 1/20 0.42
HSP90AA1 P07900 1/20 0.42
FBP1 P09467 1/20 0.41
VCP P55072 1/20 0.41
CYP19A1 P11511 1/20 0.41
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
TP53 P04637 1/20 0.40
CA1 P00915 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8000291 0.84 TSHR (0.47) TSHRLMNAGAAHTTKMT2A
SCHEMBL6683625 0.78 TSHR (0.55) TSHRLMNAGAAHTTKMT2A
SCHEMBL1018166 0.75 TSHR (0.67) TSHRLMNAGAAHTTKMT2A
SCHEMBL14983365 0.74 TSHR (0.50) TSHRLMNAGAAHTTKMT2A
SCHEMBL14983363 0.74 TSHR (0.50) TSHRLMNAGAAHTTKMT2A
SCHEMBL20312353 0.74 TSHR (0.50) TSHRLMNAGAAHTTKMT2A
SCHEMBL14983364 0.72 TSHR (0.47) TSHRLMNAGAAHTTKMT2A
SCHEMBL29758194 0.72 TSHR (0.61) TSHRLMNAGAAHTTKMT2A
SCHEMBL127723 0.72 TSHR (0.61) TSHRLMNAGAAHTTKMT2A
SCHEMBL16687390 0.72 TSHR (0.61) TSHRLMNAGAAHTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000010007-A9 DEVICES AND METHODS FOR ANALYSIS OF NON-IONIC SOLUTES CALIFORNIA INST OF TECHN (US) 2000-07-06 WO claimed
WO-2000010007-A2 DEVICES AND METHODS FOR ANALYSIS OF NON-IONIC SOLUTES CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2000-02-24 WO claimed
WO-2000010007-A9 DEVICES AND METHODS FOR ANALYSIS OF NON-IONIC SOLUTES CALIFORNIA INST OF TECHN (US) 2000-07-06 WO disclosed
WO-2000010007-A2 DEVICES AND METHODS FOR ANALYSIS OF NON-IONIC SOLUTES CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2000-02-24 WO disclosed