SCHEMBL8000291

SCHEMBL8000291

C=COB(O)c1cccc([N+](=O)[O-])c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.47
LMNA P02545 1/20 0.47
ALDH1A1 P00352 5/20 0.45
ALOX15 P16050 1/20 0.45
GAA P10253 1/20 0.42
HTT P42858 1/20 0.42
KMT2A Q03164 1/20 0.42
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
PRSS1 P07477 1/20 0.42
PRSS2 P07478 1/20 0.42
PRSS3 P35030 1/20 0.42
TP53 P04637 1/20 0.41
ACHE P22303 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CA2 P00918 2/20 0.41
CA1 P00915 1/20 0.41
MMP1 P03956 1/20 0.41
MMP2 P08253 1/20 0.41
MMP9 P14780 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7997205 0.84 TSHR (0.50) TSHRLMNAALDH1A1ALOX15GAA
SCHEMBL6500392 0.80 TSHR (0.52) TSHRLMNAALDH1A1ALOX15GAA
SCHEMBL28022638 0.80 TSHR (0.52) TSHRLMNAALDH1A1ALOX15GAA
SCHEMBL27995557 0.80 TSHR (0.52) TSHRLMNAALDH1A1ALOX15GAA
SCHEMBL13857813 0.77 TP53 (0.50) TSHRLMNAALDH1A1ALOX15GAA
SCHEMBL29758194 0.77 TSHR (0.61) TSHRLMNAALDH1A1ALOX15GAA
SCHEMBL127723 0.77 TSHR (0.61) TSHRLMNAALDH1A1ALOX15GAA
Hydrochloric Acid SCHEMBL28382242 0.75 TSHR (0.59) TSHRLMNAALDH1A1ALOX15GAA
SCHEMBL16812678 0.74 TSHR (0.57) TSHRLMNAALDH1A1ALOX15GAA
SCHEMBL28355307 0.74 TSHR (0.44) TSHRLMNAALDH1A1ALOX15GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000010007-A9 DEVICES AND METHODS FOR ANALYSIS OF NON-IONIC SOLUTES CALIFORNIA INST OF TECHN (US) 2000-07-06 WO claimed
WO-2000010007-A9 DEVICES AND METHODS FOR ANALYSIS OF NON-IONIC SOLUTES CALIFORNIA INST OF TECHN (US) 2000-07-06 WO disclosed
WO-2000010007-A2 DEVICES AND METHODS FOR ANALYSIS OF NON-IONIC SOLUTES CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2000-02-24 WO disclosed