SCHEMBL127723

SCHEMBL127723

O=[N+]([O-])c1cccc(B(O)O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.61
LMNA P02545 1/20 0.61
ALDH1A1 P00352 5/20 0.57
ALOX15 P16050 1/20 0.57
HTT P42858 2/20 0.53
KMT2A Q03164 2/20 0.53
GAA P10253 1/20 0.53
CES2 O00748 1/20 0.53
CES1 P23141 1/20 0.53
ACHE P22303 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
TP53 P04637 1/20 0.52
CA2 P00918 2/20 0.50
CA1 P00915 1/20 0.50
MMP1 P03956 1/20 0.50
MMP2 P08253 1/20 0.50
MMP9 P14780 1/20 0.50
MMP8 P22894 1/20 0.50
MMP13 P45452 1/20 0.50
HSP90AA1 P07900 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29758194 1.00 TSHR (0.61) TSHRLMNAALDH1A1ALOX15HTT
Hydrochloric Acid SCHEMBL28382242 0.98 TSHR (0.59) TSHRLMNAALDH1A1ALOX15HTT
Phosphoric Acid SCHEMBL28445592 0.93 TSHR (0.53) TSHRLMNAALDH1A1ALOX15HTT
SCHEMBL6981176 0.90 ALDH1A1 (0.66) TSHRLMNAALDH1A1ALOX15HTT
SCHEMBL1668771 0.87 TSHR (0.47) TSHRLMNAALDH1A1ALOX15HTT
Cadaverine Tartrate SCHEMBL28355308 0.87 TP53 (0.49) TSHRLMNAALDH1A1ALOX15HTT
SCHEMBL6701294 0.86 TSHR (0.46) TSHRLMNAALDH1A1ALOX15HTT
SCHEMBL16812678 0.85 TSHR (0.57) TSHRLMNAALDH1A1ALOX15HTT
SCHEMBL1018166 0.83 TSHR (0.67) TSHRLMNAALDH1A1ALOX15HTT
SCHEMBL14071499 0.82 ENPP2 (0.48) ALDH1A1CA2CA1CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3072 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720728-A1 COATED SILICONE HYDROGEL CONTACT LENSES AND METHOD FOR MAKING THE SAME Alcon Inc. (CH) 2026-04-08 EP claimed
US-20250194617-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-06-19 US claimed
US-20250169514-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-05-29 US claimed
CN-119591560-A Synthesis method of thifluzamide 湖南速博生物技术有限公司 2025-03-11 CN claimed
WO-2024241239-A1 COATED SILICONE HYDROGEL CONTACT LENSES AND METHOD FOR MAKING THE SAME ALCON INC. (CH) 2024-11-28 WO claimed
US-20240393501-A1 COATED SILICONE HYDROGEL CONTACT LENSES AND METHOD FOR MAKING THE SAME ALCON INC (CH) 2024-11-28 US claimed
CN-119019319-A Synthesis method of N, N' -bis 2, 6-tetramethyl-4-piperidinyl-1, 3-phthalamide 浙江诺驷新材料科技有限公司 2024-11-26 CN claimed
CN-118791737-A Anthracene-based fluorescent polymer and preparation method and application thereof 常州大学 2024-10-18 CN claimed
CN-118758925-A Colorimetric indicator displacement sensing array and application thereof in white tea rapid identification 集美大学 2024-10-11 CN claimed
CN-115308197-B Black tea fermentation degree judging method 安徽农业大学 2024-07-19 CN claimed
US-20020173652-A1 Process for preparing a polyaromatic compound SHASUN PHARMA SOLUTIONS, INC. 2002-11-21 US claimed
WO-2002083713-A2 ECHINOCANDIN PROCESS MERCK & CO., INC. (US) 2002-10-24 WO claimed
US-6448238-B1 BORONIC ACIDS USED WITH BETA-LACTAM ANTIBIOTICS, SUCH AS AMOXICILLIN OR CEFTAZIDIME, TO TREAT BETA-LACTAM ANTIBIOTIC RESISTANT BACTERIAL INFECTIONS NORTHWESTERN UNIVERSITY 2002-09-10 US claimed
EP-1009415-A4 INHIBITORS OF $g(b)-LACTAMASES AND USES THEREFOR UNIV NORTHWESTERN (US) 2000-10-25 EP claimed
WO-2000010007-A9 DEVICES AND METHODS FOR ANALYSIS OF NON-IONIC SOLUTES CALIFORNIA INST OF TECHN (US) 2000-07-06 WO claimed
EP-1009415-A1 INHIBITORS OF $g(b)-LACTAMASES AND USES THEREFOR NORTHWESTERN UNIVERSITY (US) 2000-06-21 EP claimed
US-6051251-A Liposome loading method using a boronic acid compound ALZA CORPORATION (US) 2000-04-18 US claimed
WO-1998056392-A1 INHIBITORS OF β-LACTAMASES AND USES THEREFOR NORTHWESTERN UNIVERSITY (US) 1998-12-17 WO claimed
EP-0626016-A1 CHEMILUMINESCENT ENHANCERS BTG INTERNATIONAL LIMITED (GB) 1994-11-30 EP claimed
WO-1993016195-A1 CHEMILUMINESCENT ENHANCERS BRITISH TECHNOLOGY GROUP LTD. (GB) 1993-08-19 WO claimed