⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL7493271 | 0.85 | BLM (0.50) | — | |
| SCHEMBL211089 | 0.78 | — | — | |
| SCHEMBL21989218 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL7809058 | 0.74 | CA1 (0.31) | — | |
| SCHEMBL19063125 | 0.72 | — | — | |
| SCHEMBL24377282 | 0.67 | FURIN (0.39) | — | |
| SCHEMBL12217939 | 0.67 | ALDH1A1 (0.39) | — | |
| SCHEMBL12240509 | 0.67 | — | — | |
| Acetone SCHEMBL1253506 | 0.67 | LMNA (0.55) | — | |
| Mitoguazone SCHEMBL11892949 | 0.64 | HRH4 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2665471-B1 | CONTROLLED RELEASE ORAL PHARMACEUTICAL DOSAGE FORMS COMPRISING MGBG | PATHOLOGICA LLC (US) | 2017-12-27 | — | — | EP | disclosed |
| US-20110213021-A1 | COMPOSITIONS AND METHODS FOR TREATING NOS-ASSOCIATED DISEASES | INDIGENE PHARMACEUTICALS, INC. (US) | 2011-09-01 | — | — | US | disclosed |
| US-20110213021-A1 | COMPOSITIONS AND METHODS FOR TREATING NOS-ASSOCIATED DISEASES | INDIGENE PHARMACEUTICALS, INC. (US) | 2011-09-01 | — | — | US | disclosed |
| EP-2174938-A1 | Quinoline derivatives for modulating DNA methylation | SuperGen, Inc. (US) | 2010-04-14 | — | — | EP | disclosed |
| WO-2009111037-A2 | COMPOSITIONS AND METHODS FOR TREATING NOS-ASSOCIATED DISEASES | INDIGENE PHARMACEUTICALS INC. (US) | 2009-09-11 | — | — | WO | disclosed |
| WO-2009049132-A1 | QUINOLINE DERIVATIVES FOR MODULATING DNA METHYLATION | SUPERGEN, INC. (US) | 2009-04-16 | — | — | WO | disclosed |
| US-5422360-A | Hydrazonoimidazolidin-4-one derivatives; treatment of diabetes and aging disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-06-06 | — | — | US | disclosed |
| EP-0531812-A1 | Maillard reaction inhibitor, process for producing it, composition containing it and the use thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-17 | — | — | EP | disclosed |