Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.49 |
| ▸ | CBFB | Q13951 | 2/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 8/20 | 0.34 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL7997390 | 0.73 | EGLN1 (0.32) | EGLN1ALDH1A1LMNA | |
| SCHEMBL31748582 | 0.67 | EGLN1 (0.38) | EGLN1CBFBHRH4DHODHPARP1 | |
| SCHEMBL1192719 | 0.66 | EGLN1 (1.00) | EGLN1 | |
| SCHEMBL3469733 | 0.66 | CBFB (0.44) | EGLN1CBFBHRH4ALDH1A1LMNA | |
| SCHEMBL31748504 | 0.65 | EGLN1 (0.44) | EGLN1HRH4DHODH | |
| SCHEMBL29946251 | 0.60 | EIF4A3 (0.57) | ALDH1A1LMNA | |
| SCHEMBL22395159 | 0.60 | EIF4A3 (0.57) | ALDH1A1LMNA | |
| Bicarbonate SCHEMBL16932539 | 0.59 | CA1 (0.52) | LMNA | |
| Bicarbonate SCHEMBL21630455 | 0.59 | CA1 (0.52) | LMNA | |
| Bicarbonate SCHEMBL28819166 | 0.59 | CA1 (0.52) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001083457-A2 | BENZIMIDAZOLE-2-CARBAMATES AND THEIR USE IN CANCER TREATMENT | THE PROCTER & GAMBLE COMPANY (US) | 2001-11-08 | — | — | WO | disclosed |