Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBFB | Q13951 | 2/20 | 0.44 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31748611 | 0.85 | PSMB8 (0.41) | CBFBPSMB8EGLN1DHODH | |
| SCHEMBL5904354 | 0.74 | PSMB8 (0.54) | CBFBPSMB8EGLN1HRH4ALDH1A1 | |
| SCHEMBL3469735 | 0.71 | PSMB8 (0.40) | PSMB8 | |
| SCHEMBL9172104 | 0.67 | CACNA1H (0.56) | EGLN1 | |
| SCHEMBL9391888 | 0.66 | RIPK1 (0.53) | CBFBPSMB8EGLN1 | |
| SCHEMBL23449132 | 0.66 | PSMB8 (0.41) | PSMB8 | |
| SCHEMBL1832199 | 0.64 | PSMB8 (0.65) | CBFBPSMB8 | |
| SCHEMBL251067 | 0.62 | PSMB8 (0.67) | PSMB8 | |
| SCHEMBL20094244 | 0.62 | CBFB (0.51) | CBFBEGLN1HRH4ALDH1A1 | |
| SCHEMBL1192621 | 0.62 | EGLN1 (0.54) | CBFBEGLN1HRH4ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069519-A1 | TOPICAL COMPOSITIONS COMPRISING AT LEAST ONE ACTIVE INGREDIENT POORLY SOLUBLE IN WATER AND BIOPOLYMERS SUCH AS HYALURONIC ACID WITH A PKA-VALUE BETWEEN 5-7 | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-24 | — | — | WO | disclosed |