Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 3/20 | 0.64 |
| ▸ | DRD2 | P14416 | 2/20 | 0.64 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.64 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.64 |
| ▸ | HTR1A | P08908 | 1/20 | 0.64 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.64 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.64 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.64 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.64 |
| ▸ | DRD4 | P21917 | 1/20 | 0.64 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.64 |
| ▸ | HRH1 | P35367 | 1/20 | 0.64 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4061569 | 0.99 | CHRM1 (0.65) | CHRM1DRD2CHRM2CHRM4HTR1A | |
| SCHEMBL4495358 | 0.94 | CHRM1 (0.59) | CHRM1DRD2CHRM2CHRM4HTR1A | |
| SCHEMBL4492882 | 0.90 | CHRM1 (0.56) | CHRM1DRD2CHRM2CHRM4HTR1A | |
| SCHEMBL4500024 | 0.87 | CHRM1 (0.53) | CHRM1DRD2CHRM2CHRM4HTR1A | |
| SCHEMBL7752363 | 0.85 | S1PR1 (0.49) | CHRM1DRD2CHRM2CHRM4HTR1A | |
| SCHEMBL4504348 | 0.78 | DRD2 (1.00) | CHRM1DRD2CHRM2CHRM4HTR1A | |
| SCHEMBL31060842 | 0.78 | DRD2 (1.00) | CHRM1DRD2CHRM2CHRM4HTR1A | |
| Hydrochloric Acid SCHEMBL4171949 | 0.77 | CHRM1 (1.00) | CHRM1DRD2CHRM2CHRM4HTR1A | |
| SCHEMBL7151613 | 0.77 | CHRM1 (0.76) | CHRM1DRD2CHRM2CHRM4HTR1A | |
| SCHEMBL4501010 | 0.76 | DRD2 (0.75) | CHRM1DRD2CHRM2CHRM4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001005763-A2 | COMPOUNDS WITH ACTIVITY ON MUSCARINIC RECEPTORS | ACADIA PHARMACEUTICALS, INC. (US) | 2001-01-25 | — | — | WO | disclosed |