Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.49 |
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997393 | 0.85 | CHRM1 (0.64) | S1PR1S1PR3S1PR5ALDH1A1ADRA1D | |
| Hydrochloric Acid SCHEMBL4061569 | 0.84 | CHRM1 (0.65) | S1PR1S1PR3S1PR5ALDH1A1ADRA1D | |
| SCHEMBL6103069 | 0.80 | ALDH1A1 (0.52) | SCN1ASCN2ASCN3AALDH1A1KMT2A | |
| SCHEMBL8699135 | 0.79 | TBXAS1 (0.58) | ALDH1A1KMT2AHCRTR1HCRTR2ADRA1D | |
| SCHEMBL4495358 | 0.79 | CHRM1 (0.59) | S1PR1S1PR3S1PR5ALDH1A1ADRA1D | |
| Acetic Acid SCHEMBL30330118 | 0.78 | S1PR1 (0.63) | S1PR1S1PR3S1PR5OPRD1 | |
| Acetic Acid SCHEMBL30329995 | 0.77 | S1PR1 (0.65) | S1PR1S1PR3S1PR5OPRD1 | |
| Acetic Acid SCHEMBL29251582 | 0.77 | S1PR1 (0.65) | S1PR1S1PR3S1PR5OPRD1 | |
| SCHEMBL4509670 | 0.77 | CHRM1 (0.72) | ADRA1DADRA1AADRA1BCHRM1CHRM2 | |
| SCHEMBL7029673 | 0.76 | S1PR1 (0.61) | S1PR1S1PR3S1PR5OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001005763-A2 | COMPOUNDS WITH ACTIVITY ON MUSCARINIC RECEPTORS | ACADIA PHARMACEUTICALS, INC. (US) | 2001-01-25 | — | — | WO | disclosed |
| EP-1068185-A1 | COMPOUNDS WITH ACTIVITY ON MUSCARINIC RECEPTORS | Acadia Pharmaceuticals Inc. (US) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999050247-A1 | COMPOUNDS WITH ACTIVITY ON MUSCARINIC RECEPTORS | ACADIA PHARMACEUTICALS, INC. (US) | 1999-10-07 | — | — | WO | disclosed |