Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2716493 | 0.86 | PTGER1 (0.48) | PTGER1ALDH1A1TSHRKDM4EHSD17B10 | |
| SCHEMBL477006 | 0.85 | ALDH1A1 (0.59) | ALDH1A1TSHRDHODHKDM4EHSD17B10 | |
| SCHEMBL8086389 | 0.84 | MAPK1 (0.49) | PTGER1ALDH1A1TSHRDHODHTP53 | |
| SCHEMBL8417183 | 0.84 | TP53 (0.50) | PTGER1ALDH1A1TSHRDHODHTP53 | |
| Benzene SCHEMBL28043964 | 0.83 | ALDH1A1 (0.57) | ALDH1A1TSHRDHODHKDM4EHSD17B10 | |
| SCHEMBL17799583 | 0.83 | ALDH1A1 (0.57) | ALDH1A1TSHRDHODHKDM4EHSD17B10 | |
| Bicarbonate SCHEMBL29943829 | 0.83 | ALDH1A1 (0.57) | ALDH1A1TSHRDHODHKDM4EHSD17B10 | |
| Bicarbonate SCHEMBL20694841 | 0.83 | ALDH1A1 (0.57) | ALDH1A1TSHRDHODHKDM4EHSD17B10 | |
| Bicarbonate SCHEMBL236893 | 0.83 | ALDH1A1 (0.57) | ALDH1A1TSHRDHODHKDM4EHSD17B10 | |
| SCHEMBL20428770 | 0.82 | LTB4R (0.45) | PTGER1ALDH1A1KDM4EHSD17B10MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |