Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3439958 | 0.87 | ALDH1A1 (0.44) | ALDH1A1P2RX7LMNAPOLBRXFP1 | |
| SCHEMBL17220667 | 0.87 | LMNA (0.48) | ALDH1A1P2RX7LMNAPOLBRXFP1 | |
| SCHEMBL3439960 | 0.86 | ALDH1A1 (0.43) | ALDH1A1P2RX7LMNAPOLBRXFP1 | |
| SCHEMBL476879 | 0.81 | ALDH1A1 (0.66) | ALDH1A1P2RX7LMNAPOLBTSHR | |
| SCHEMBL6384294 | 0.80 | LCK (0.43) | ALDH1A1P2RX7LMNAPOLBRXFP1 | |
| SCHEMBL7997788 | 0.80 | ALDH1A1 (0.44) | ALDH1A1LMNAPOLBGPR35 | |
| SCHEMBL5866194 | 0.79 | HSP90AA1 (0.46) | ALDH1A1P2RX7LMNAPOLBRXFP1 | |
| SCHEMBL9687284 | 0.79 | ALDH1A1 (0.50) | ALDH1A1LMNAPOLBTSHRHTT | |
| SCHEMBL17230181 | 0.78 | CYP1A2 (0.45) | ALDH1A1LMNAPOLBBRD4BRD9 | |
| SCHEMBL17230173 | 0.78 | CYP1A2 (0.45) | ALDH1A1LMNAPOLBBRD4NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |