Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.61 |
| ▸ | F2 | P00734 | 5/20 | 0.50 |
| ▸ | PLG | P00747 | 4/20 | 0.49 |
| ▸ | PROC | P04070 | 1/20 | 0.49 |
| ▸ | PLAT | P00750 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996090 | 0.93 | F10 (0.57) | F10F2PLGPROCPLAT | |
| SCHEMBL7999868 | 0.88 | F10 (0.74) | F10F2PLGPROC | |
| SCHEMBL7997631 | 0.88 | F10 (0.63) | F10F2PLGPROCPRSS1 | |
| Hydrochloric Acid SCHEMBL6895363 | 0.88 | F10 (0.73) | F10F2PLGPROC | |
| SCHEMBL7996212 | 0.85 | F10 (0.62) | F10F2PLGPROC | |
| SCHEMBL1652451 | 0.83 | F10 (0.61) | F10F2PLGPROC | |
| SCHEMBL1651311 | 0.82 | F10 (0.65) | F10F2PLGPROCPRSS1 | |
| SCHEMBL7999914 | 0.82 | F10 (0.63) | F10F2PLGPROC | |
| SCHEMBL7999713 | 0.82 | F10 (0.62) | F10F2PLGPROC | |
| SCHEMBL1654292 | 0.82 | F10 (0.75) | F10F2PLGPROCPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000008005-A2 | PIPERAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-02-17 | — | — | WO | disclosed |