Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.57 |
| ▸ | F2 | P00734 | 3/20 | 0.49 |
| ▸ | PLG | P00747 | 3/20 | 0.49 |
| ▸ | PLAT | P00750 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PROC | P04070 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997638 | 0.93 | F10 (0.61) | F10F2PLGPLATPRSS1 | |
| SCHEMBL8003156 | 0.88 | F10 (0.61) | F10F2PLGPRSS1PROC | |
| Hydrochloric Acid SCHEMBL6896958 | 0.87 | F10 (0.61) | F10F2PLGPRSS1PROC | |
| SCHEMBL1303308 | 0.85 | F10 (0.71) | F10F2 | |
| Hydrochloric Acid SCHEMBL6895022 | 0.84 | F10 (0.70) | F10F2 | |
| SCHEMBL7986949 | 0.82 | F10 (0.58) | F10F2 | |
| SCHEMBL7996139 | 0.81 | F10 (0.54) | F10F2PLGPROC | |
| SCHEMBL7999873 | 0.81 | F10 (0.61) | F10F2PLGPLATPRSS1 | |
| SCHEMBL7999868 | 0.81 | F10 (0.74) | F10F2PLGPROC | |
| SCHEMBL7986862 | 0.81 | F10 (0.57) | F10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000008005-A2 | PIPERAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-02-17 | — | — | WO | disclosed |