Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983840 | 0.90 | KLKB1 (0.38) | MAPTALDH1A1SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL7983883 | 0.83 | SCN9A (0.43) | KLKB1 | |
| SCHEMBL7998248 | 0.82 | KLKB1 (0.35) | ALDH1A1KLKB1 | |
| SCHEMBL7994180 | 0.82 | KLKB1 (0.39) | SMN1; SMN2KLKB1 | |
| SCHEMBL7983762 | 0.75 | SCN9A (0.44) | — | |
| SCHEMBL7998407 | 0.72 | STING1 (0.41) | MAPTL3MBTL1 | |
| SCHEMBL10287892 | 0.71 | SMN1; SMN2 (0.56) | MAPTALDH1A1HTTNPSR1LMNA | |
| SCHEMBL7995743 | 0.70 | STING1 (0.41) | L3MBTL1MEN1KMT2A | |
| SCHEMBL16063127 | 0.70 | SMN1; SMN2 (0.71) | MAPTALDH1A1HTTNPSR1LMNA | |
| SCHEMBL18377475 | 0.69 | KLKB1 (0.56) | CYP3A4CYP2C9CYP2C19KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |