Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997642 | 0.90 | MAPT (0.42) | KLKB1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7983883 | 0.89 | SCN9A (0.43) | KLKB1 | |
| SCHEMBL7994180 | 0.88 | KLKB1 (0.39) | KLKB1SMN1; SMN2HPGDSMYD3 | |
| SCHEMBL7998248 | 0.88 | KLKB1 (0.35) | KLKB1HTR1BALDH1A1SMYD3 | |
| SCHEMBL7983762 | 0.81 | SCN9A (0.44) | — | |
| SCHEMBL7998407 | 0.78 | STING1 (0.41) | MAPTSMYD3 | |
| SCHEMBL7995743 | 0.75 | STING1 (0.41) | MEN1KMT2A | |
| SCHEMBL7995439 | 0.73 | KDM4E (0.49) | NPC1RAB9ASMN1; SMN2HTR1BALDH1A1 | |
| SCHEMBL7997358 | 0.72 | MEN1 (0.46) | NPC1RAB9ASMN1; SMN2HTR1BALDH1A1 | |
| SCHEMBL8001602 | 0.72 | ALDH1A1 (0.38) | KLKB1NPC1RAB9AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |