SCHEMBL7997765

SCHEMBL7997765

Cc1c(CCl)cccc1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PREP P48147 1/20 0.33
DRD2 P14416 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3149357 0.85 RIPK1 (0.35) PREP
SCHEMBL16456193 0.84 PDCD1 (0.41) PREPDRD2
SCHEMBL16501188 0.78 MAPT (0.42)
SCHEMBL2905195 0.76 PREP (0.33) PREPDRD2
SCHEMBL7247912 0.75 TSHR (0.45) PREP
SCHEMBL17621111 0.75 CYP2D6 (0.33) PREP
SCHEMBL9860753 0.73 IDO1 (0.42)
SCHEMBL30951646 0.73 IDO1 (0.42)
SCHEMBL7240943 0.73 RIPK1 (0.36) PREPDRD2
SCHEMBL2325955 0.73 RIPK1 (0.36) PREPDRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001034578-A1 COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY ASTRAZENECA AB (SE) 2001-05-17 WO disclosed