SCHEMBL3149357

SCHEMBL3149357

CC(C)(C)[Si](C)(C)Oc1ccccc1CCl

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 2/20 0.35
IDO1 P14902 2/20 0.34
HTT P42858 1/20 0.33
PREP P48147 2/20 0.32
BACE1 P56817 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
CA12 O43570 2/20 0.30
CA1 P00915 2/20 0.30
CA9 Q16790 2/20 0.30
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30
CHRM2 P08172 1/20 0.30
CHRM1 P11229 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7997765 0.85 PREP (0.33) PREP
SCHEMBL15283292 0.84 RIPK1 (0.36) RIPK1IDO1HTTPREPBACE1
SCHEMBL9853837 0.84 L3MBTL1 (0.44) RIPK1IDO1PREPSLC6A2SLC6A4
SCHEMBL2325955 0.84 RIPK1 (0.36) RIPK1IDO1HTTPREPBACE1
SCHEMBL7240943 0.84 RIPK1 (0.36) RIPK1IDO1HTTPREPBACE1
SCHEMBL30039264 0.82 CYP4F2 (0.36) RIPK1IDO1HTTBACE1CA12
SCHEMBL6943654 0.82 CYP4F2 (0.36) RIPK1IDO1HTTBACE1CA12
SCHEMBL3155841 0.81 IDO1 (0.34) RIPK1IDO1ALDH1A1TSHRTAAR1
SCHEMBL8700617 0.81 ADRA2A (0.41) RIPK1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL7134633 0.81 BACE1 (0.43) RIPK1IDO1HTTPREPBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2154123-B1 METHOD FOR PRODUCING BENZALDEHYDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2013-10-23 EP disclosed
US-7851659-B2 Method for producing benzaldehyde compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-12-14 US disclosed
US-20100234645-A1 METHOD FOR PRODUCING BENZALDEHYDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-09-16 US disclosed
EP-2154123-A1 METHOD FOR PRODUCING BENZALDEHYDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2010-02-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100234645-A1 METHOD FOR PRODUCING BENZALDEHYDE COMPOUND NQO1, NQO2, NDUFC2 RIPK1 4753/4885IDO1 395/4885HTT 2486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.