Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 20/20 | 0.50 |
| ▸ | RXRG | P48443 | 13/20 | 0.50 |
| ▸ | RXRB | P28702 | 13/20 | 0.41 |
| ▸ | RARG | P13631 | 5/20 | 0.40 |
| ▸ | RARB | P10826 | 4/20 | 0.39 |
| ▸ | RARA | P10276 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996046 | 0.79 | RXRA (0.42) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL8008143 | 0.76 | RXRA (0.47) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL8005836 | 0.75 | RXRA (0.59) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL6917451 | 0.74 | RXRA (0.46) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL28533078 | 0.72 | RXRA (0.64) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL7622765 | 0.72 | RXRA (0.48) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL9124020 | 0.71 | RXRA (0.50) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL6915032 | 0.71 | RXRA (0.47) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL8632485 | 0.71 | RXRA (0.48) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL11599145 | 0.69 | RXRA (0.42) | RXRARXRGRXRBRARGRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000026173-A1 | NOVEL RETINOIDS, METHODS FOR THEIR PRODUCTION AND USE | LIGAND PHARMACEUTICALS INCORPORATED (DE) | 2000-05-11 | — | — | WO | disclosed |
| US-6005007-A | SKIN DISORDERS | LIGAND PHARMACEUTICALS INCORPORATED | 1999-12-21 | — | — | US | disclosed |