Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 13/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | RARA | P10276 | 7/20 | 0.39 |
| ▸ | RARB | P10826 | 7/20 | 0.39 |
| ▸ | RARG | P13631 | 7/20 | 0.39 |
| ▸ | RXRG | P48443 | 6/20 | 0.39 |
| ▸ | RXRB | P28702 | 4/20 | 0.39 |
| ▸ | HNF4A | P41235 | 3/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8008143 | 0.85 | RXRA (0.47) | RXRARARARARBRARGRXRG | |
| SCHEMBL6917451 | 0.82 | RXRA (0.46) | RXRARARARARBRARGRXRG | |
| SCHEMBL6915032 | 0.79 | RXRA (0.47) | RXRARARARARBRARGRXRG | |
| SCHEMBL7997835 | 0.79 | RXRA (0.50) | RXRARARARARBRARGRXRG | |
| SCHEMBL8421087 | 0.77 | RXRA (0.41) | RXRAALOX15RARARARBRARG | |
| SCHEMBL15348324 | 0.75 | RXRA (0.51) | RXRAALOX15RARARARBRARG | |
| SCHEMBL11220334 | 0.73 | ALOX15 (0.51) | RXRAALOX15RARARARBRARG | |
| SCHEMBL7735393 | 0.70 | RXRA (0.73) | RXRARARARARBRARGRXRG | |
| SCHEMBL7735391 | 0.70 | RXRA (0.73) | RXRARARARARBRARGRXRG | |
| SCHEMBL7996044 | 0.70 | RXRA (0.43) | RXRAALOX15RARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000026173-A1 | NOVEL RETINOIDS, METHODS FOR THEIR PRODUCTION AND USE | LIGAND PHARMACEUTICALS INCORPORATED (DE) | 2000-05-11 | — | — | WO | disclosed |
| US-6005007-A | SKIN DISORDERS | LIGAND PHARMACEUTICALS INCORPORATED | 1999-12-21 | — | — | US | disclosed |