Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8744098 | 1.00 | STAT3 (0.54) | STAT3HTTTSHRCASP1KDM4E | |
| SCHEMBL4672032 | 0.93 | STAT3 (0.62) | STAT3HTTTSHRCASP1KDM4E | |
| SCHEMBL8539874 | 0.93 | STAT3 (0.62) | STAT3HTTTSHRCASP1KDM4E | |
| SCHEMBL9096244 | 0.93 | STAT3 (0.62) | STAT3HTTTSHRCASP1KDM4E | |
| SCHEMBL13483600 | 0.89 | STAT3 (0.52) | STAT3HTTTSHRCASP1KDM4E | |
| SCHEMBL8111555 | 0.86 | STAT3 (0.56) | STAT3HTTTSHRCASP1KDM4E | |
| SCHEMBL4671582 | 0.86 | STAT3 (0.46) | STAT3HTTTSHRCASP1KDM4E | |
| SCHEMBL13483601 | 0.86 | STAT3 (0.48) | STAT3HTTTSHRCASP1KDM4E | |
| SCHEMBL7997875 | 0.85 | GSK3B (0.45) | STAT3HTTKDM4EALDH1A1CYP1A2 | |
| SCHEMBL8744082 | 0.85 | GSK3B (0.45) | STAT3HTTKDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593766-B1 | PYRIDONECARBOXYLIC ACID DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2000-09-06 | — | — | EP | disclosed |
| US-5696132-A | MICROBIOCIDES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-12-09 | — | — | US | disclosed |
| EP-0593766-A1 | PYRIDONECARBOXYLIC ACID DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |