Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.45 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8009751 | 0.90 | ALDH1A1 (0.49) | ALDH1A1NPC1RAB9AMAPTHTT | |
| SCHEMBL4596654 | 0.80 | MAPKAPK2 (0.53) | ALDH1A1RAB9AMAPKAPK2RPS6KA3CSNK2A1 | |
| SCHEMBL8009431 | 0.78 | ALDH1A1 (0.50) | ALDH1A1NPC1RAB9AMAPTHTT | |
| SCHEMBL11520368 | 0.77 | MAPKAPK2 (0.58) | ALDH1A1MAPTKDM4EMAPKAPK2RPS6KA3 | |
| SCHEMBL6176174 | 0.73 | ALDH1A1 (0.57) | ALDH1A1NPC1RAB9AMAPTHTT | |
| SCHEMBL6175342 | 0.72 | ALDH1A1 (0.64) | ALDH1A1NPC1RAB9AMAPTHTT | |
| SCHEMBL6177938 | 0.72 | ALDH1A1 (0.59) | ALDH1A1NPC1RAB9AMAPTHTT | |
| SCHEMBL6176543 | 0.71 | ALDH1A1 (0.62) | ALDH1A1NPC1RAB9AMAPTHTT | |
| SCHEMBL6175116 | 0.71 | ALDH1A1 (0.55) | ALDH1A1NPC1RAB9AMAPTHTT | |
| SCHEMBL6173806 | 0.71 | ALDH1A1 (0.66) | ALDH1A1NPC1RAB9AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6165941-A | Substituted 2-phenylpyridines | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-26 | — | — | US | disclosed |
| EP-0708769-A1 | SUBSTITUTED 2-FUSED PHENYLPYRIDINES WITH HERBICIDAL ACTIVITY | BASF AKTIENGESELLSCHAFT (DE) | 1996-05-01 | — | — | EP | disclosed |
| WO-1995002590-A2 | SUBSTITUTED 2-FUSED PHENYLPYRIDINES WITH HERBICIDAL ACTIVITIES | BASF AKTIENGESELLSCHAFT (DE) | 1995-01-26 | — | — | WO | disclosed |