Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997937 | 0.88 | ADRB2 (0.38) | LMNAADRB2ADRB1ADRB3TSHR | |
| SCHEMBL2913836 | 0.81 | LMNA (0.36) | LMNAADRB2ADRB1ADRB3TSHR | |
| SCHEMBL20678519 | 0.80 | — | — | |
| SCHEMBL5552630 | 0.79 | LMNA (0.39) | LMNAADRB2ADRB1ADRB3TSHR | |
| SCHEMBL16497215 | 0.79 | LMNA (0.44) | LMNAADRB2ADRB1ADRB3TSHR | |
| SCHEMBL16497480 | 0.79 | LMNA (0.44) | LMNAADRB2ADRB1ADRB3TSHR | |
| SCHEMBL1609072 | 0.76 | LMNA (0.33) | LMNAADRB2ADRB1ADRB3 | |
| SCHEMBL56348 | 0.75 | — | — | |
| SCHEMBL1608805 | 0.74 | LMNA (0.39) | LMNATSHR | |
| SCHEMBL27955448 | 0.74 | LMNA (0.39) | LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834536-A | REACTING HALOGENATED ALKYL SILANE WITH INORGANIC POLYSULFIDE IN PRESENCE OF WATER AND FILLER(CARRIER) FIBERS OR PARTICLES, THEN DRYING BEFORE MIXING INTO RUBBER; FOR HEAT RESISTANT TIRES HAVING LOW ROLLING RESISTANCE | BAYER AG (DE) | 1998-11-10 | — | — | US | claimed |
| US-6277902-B1 | RUBBER COMPOUNDS COMPRISING SOLUBLE RUBBER, HYDROPHOBIZED FILLER HAVING SPECIFIED METHANOL WETTABILITY, SUPPORTEDPOLYSULFIDIC-SILANE COMPOUNDS PREPARED BY REACTION OF HALOALKYLSILANES, ORGANIC HALOGEN COMPOUNDS AND POLYSULFIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-21 | — | — | US | disclosed |
| US-5834536-A | REACTING HALOGENATED ALKYL SILANE WITH INORGANIC POLYSULFIDE IN PRESENCE OF WATER AND FILLER(CARRIER) FIBERS OR PARTICLES, THEN DRYING BEFORE MIXING INTO RUBBER; FOR HEAT RESISTANT TIRES HAVING LOW ROLLING RESISTANCE | BAYER AG (DE) | 1998-11-10 | — | — | US | disclosed |