Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 13/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8003234 | 0.75 | PARP1 (0.46) | PARP1PDE10ACYP1A2PDE4DALDH1A1 | |
| SCHEMBL8003231 | 0.75 | PARP1 (0.46) | PARP1PDE10ACYP1A2PDE4DALDH1A1 | |
| SCHEMBL27830249 | 0.68 | SMN1; SMN2 (0.44) | CYP1A2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL14200056 | 0.67 | CASP1 (0.49) | CYP1A2ALDH1A1 | |
| SCHEMBL14200054 | 0.67 | CASP1 (0.49) | CYP1A2ALDH1A1 | |
| SCHEMBL13001768 | 0.67 | CASP1 (0.49) | CYP1A2ALDH1A1 | |
| SCHEMBL20845592 | 0.67 | PARP1 (0.74) | PARP1PDE10AKDM4EALDH1A1HPGD | |
| SCHEMBL27926381 | 0.66 | PARP1 (0.72) | PARP1PDE10AKDM4EALDH1A1HPGD | |
| SCHEMBL1101005 | 0.66 | PARP1 (0.58) | PARP1PDE10ACYP1A2PDE4DKDM4E | |
| SCHEMBL27811623 | 0.65 | PDE10A (0.53) | PARP1PDE10AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000015617-A1 | 2-AMINOETHYL-QUINOLINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE | SANOFI-SYNTHELABO (FR) | 2000-03-23 | — | — | WO | disclosed |