Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | HPGDS | O60760 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.46 |
| ▸ | SCN4A | P35499 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27944783 | 0.83 | LTA4H (0.56) | RAB9APOLBNPC1MAPTSCN4A | |
| SCHEMBL7998222 | 0.83 | PDPK1 (0.47) | RAB9APOLBALDH1A1MAPTTNIK | |
| SCHEMBL27944787 | 0.81 | KMT2A (0.61) | RAB9APOLBNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1531261 | 0.81 | MKNK1 (0.61) | RAB9APOLBNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5837879 | 0.81 | AXL (0.58) | RAB9APOLBNPC1ALOX15TNIK | |
| SCHEMBL18218782 | 0.81 | SMN1; SMN2 (0.61) | RAB9APOLBNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL69492 | 0.79 | MEN1 (0.58) | RAB9APOLBNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL17280251 | 0.79 | RAB9A (0.87) | RAB9APOLBNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL17858741 | 0.78 | NPC1 (0.49) | RAB9APOLBNPC1SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1221862 | 0.78 | MEN1 (0.57) | RAB9APOLBNPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4103281-A1 | PIKFYVE KINASE INHIBITORS | Acurastem Inc. (US) | 2022-12-21 | — | — | EP | disclosed |
| CN-103351341-A | Organic metal chelate, its preparation method and application | CHIEN SHIUNG INST TECHNOLOGY | 2013-10-16 | — | — | CN | disclosed |
| WO-2000027394-A1 | ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE | UNIVERSITY COLLEGE LONDON (GB) | 2000-05-18 | — | — | WO | disclosed |
| US-5679699-A | ANTIISCHEMIC AGENTS, HEART RATE LOWERING AGENTS | KALI-CHEMIE PHARMA GMBH (DE) | 1997-10-21 | — | — | US | disclosed |
| US-5547967-A | HYPOTENSIVE AGENT, ANTIISCHEMIC AGENT | KALI-CHEMIE PHARMA GMBH (DE) | 1996-08-20 | — | — | US | disclosed |
| CN-1109051-A | 3-(phenylalkyl aminoalkyloxy)-5-phenlpyrazol, production, medium and pharmaceutical of same | KALI CHEMIE PHARMA GMBH (DE) | 1995-09-27 | — | — | CN | disclosed |
| US-4695566-A | 3-aminocarbonylmethoxy-5-phenylpyrazole compounds, antiarrythmic compositions containing them, and intermediates in their preparation | KALI-CHEMIE PHARMA GMBH (DE) | 1987-09-22 | — | — | US | disclosed |