Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA4 | P22748 | 3/20 | 0.44 |
| ▸ | CA5A | P35218 | 3/20 | 0.44 |
| ▸ | CA7 | P43166 | 3/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4186934 | 0.90 | LGALS8 (0.56) | MEN1CYP3A4KMT2ATP53CYP2C9 | |
| SCHEMBL23121475 | 0.90 | LGALS8 (0.50) | MEN1CYP3A4KMT2ATP53CYP2C9 | |
| SCHEMBL4186930 | 0.90 | LGALS8 (0.56) | MEN1CYP3A4KMT2ATP53CYP2C9 | |
| SCHEMBL7998399 | 0.88 | TSHR (0.49) | MEN1CYP3A4KMT2ATP53LGALS8 | |
| SCHEMBL7945964 | 0.87 | CYP3A4 (0.65) | MEN1CYP3A4KMT2ATP53CYP2C9 | |
| SCHEMBL22073058 | 0.87 | CYP3A4 (0.65) | MEN1CYP3A4KMT2ATP53CYP2C9 | |
| SCHEMBL4182296 | 0.87 | CYP3A4 (0.65) | MEN1CYP3A4KMT2ATP53CYP2C9 | |
| SCHEMBL22710592 | 0.87 | CYP3A4 (0.65) | MEN1CYP3A4KMT2ATP53CYP2C9 | |
| SCHEMBL16689628 | 0.87 | CYP3A4 (0.65) | MEN1CYP3A4KMT2ATP53CYP2C9 | |
| SCHEMBL18022553 | 0.87 | CYP3A4 (0.65) | MEN1CYP3A4KMT2ATP53CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294521-B1 | SUGAR PHOSPHATES | AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2001-09-25 | — | — | US | disclosed |