Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA4 | P22748 | 3/20 | 0.45 |
| ▸ | CA5A | P35218 | 3/20 | 0.45 |
| ▸ | CA7 | P43166 | 3/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.45 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16755654 | 0.88 | ALDH1A1 (0.43) | CA12CA1CA2CA4CA5A | |
| SCHEMBL7998397 | 0.88 | MEN1 (0.54) | CA12CA1CA2CA4CA5A | |
| SCHEMBL16847689 | 0.87 | TSHR (0.67) | TSHRALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL7694818 | 0.87 | TSHR (0.67) | TSHRALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL4609421 | 0.87 | TSHR (0.67) | TSHRALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL24598883 | 0.87 | TSHR (0.67) | TSHRALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL7694820 | 0.87 | TSHR (0.67) | TSHRALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL4609383 | 0.87 | TSHR (0.67) | TSHRALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL29307027 | 0.87 | TSHR (0.67) | TSHRALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL313492 | 0.87 | TSHR (0.67) | TSHRALDH1A1LMNAPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294521-B1 | SUGAR PHOSPHATES | AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2001-09-25 | — | — | US | disclosed |