Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 16/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | IRF3 | Q14653 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983874 | 0.85 | STING1 (0.43) | STING1L3MBTL1KDM4EALDH1A1LMNA | |
| SCHEMBL7983909 | 0.76 | SMN1; SMN2 (0.49) | KDM4EALDH1A1LMNAMAPTHTT | |
| SCHEMBL7983841 | 0.74 | SMN1; SMN2 (0.50) | ALDH1A1LMNAMAPTHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8001463 | 0.74 | SMN1; SMN2 (0.49) | ALDH1A1LMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL7994647 | 0.74 | SMN1; SMN2 (0.49) | ALDH1A1LMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL7983724 | 0.73 | SMN1; SMN2 (0.55) | L3MBTL1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL7995844 | 0.73 | SMN1; SMN2 (0.48) | KDM4EALDH1A1LMNAMAPTHTT | |
| SCHEMBL7994205 | 0.73 | SMN1; SMN2 (0.43) | L3MBTL1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL7983835 | 0.72 | SMN1; SMN2 (0.47) | ALDH1A1LMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL7984304 | 0.72 | STING1 (0.49) | STING1L3MBTL1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |