Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 20/20 | 0.72 |
| ▸ | MMP2 | P08253 | 19/20 | 0.72 |
| ▸ | MMP1 | P03956 | 12/20 | 0.72 |
| ▸ | MMP3 | P08254 | 1/20 | 0.53 |
| ▸ | MMP7 | P09237 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8001929 | 0.84 | MMP9 (0.71) | MMP9MMP2MMP1 | |
| SCHEMBL8002744 | 0.84 | MMP2 (1.00) | MMP9MMP2MMP1 | |
| SCHEMBL8002778 | 0.80 | MMP9 (0.71) | MMP9MMP2MMP1 | |
| SCHEMBL7670713 | 0.80 | MMP2 (0.83) | MMP9MMP2MMP1 | |
| SCHEMBL8003465 | 0.80 | MMP2 (0.73) | MMP9MMP2MMP1 | |
| SCHEMBL7998626 | 0.80 | MMP9 (0.56) | MMP9MMP2MMP1MMP3MMP7 | |
| SCHEMBL8000486 | 0.79 | MMP2 (1.00) | MMP9MMP2MMP1 | |
| SCHEMBL8002034 | 0.77 | MMP2 (1.00) | MMP9MMP2MMP1 | |
| SCHEMBL10021363 | 0.76 | MMP9 (0.74) | MMP9MMP2MMP1 | |
| SCHEMBL7998781 | 0.75 | MMP2 (0.84) | MMP9MMP2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294573-B1 | FOR THERAPY RHEUMATOID ARTHRITIS, OSTEOARTHRITIS, OSTEOPENIAS SUCH AS OSTEOPOROSIS, PERIODONTITIS, GINGIVITIS, CORNEAL, EPIDERMAL OR GASTRIC ULCERATION, AND TUMOR GROWTH AND METASTASIS OR INVASION | ABBOTT LABORATORIES | 2001-09-25 | — | — | US | claimed |
| US-6294573-B1 | FOR THERAPY RHEUMATOID ARTHRITIS, OSTEOARTHRITIS, OSTEOPENIAS SUCH AS OSTEOPOROSIS, PERIODONTITIS, GINGIVITIS, CORNEAL, EPIDERMAL OR GASTRIC ULCERATION, AND TUMOR GROWTH AND METASTASIS OR INVASION | ABBOTT LABORATORIES | 2001-09-25 | — | — | US | disclosed |