Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7912417 | 0.81 | DNMT1 (0.82) | DNMT1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL19230419 | 0.78 | DNMT1 (0.83) | DNMT1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16144677 | 0.76 | DNMT1 (0.80) | DNMT1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5193172 | 0.75 | DNMT1 (0.53) | DNMT1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28712105 | 0.74 | APAF1 (0.46) | DNMT1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7122517 | 0.72 | DNMT1 (0.73) | DNMT1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL25253593 | 0.71 | HPRT1 (0.58) | DNMT1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1055754 | 0.71 | DNMT1 (1.00) | DNMT1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL31174009 | 0.71 | DNMT1 (1.00) | DNMT1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2175783 | 0.71 | DNMT1 (0.92) | DNMT1ALDH1A1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294380-B1 | Liver cell clones for use in extracorporeal liver-assist device | JMS CO., LTD. (JP) | 2001-09-25 | — | — | US | disclosed |
| EP-1063289-A1 | Liver cell clones for artifical liver and extracorporeal liver assist device | JMS Co., Ltd. (JP) | 2000-12-27 | — | — | EP | disclosed |