Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 11/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | STS | P08842 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27493817 | 0.84 | SRD5A1 (0.49) | TRPV1SRD5A1PPARA | |
| SCHEMBL13930556 | 0.78 | SRD5A1 (0.47) | TRPV1SRD5A1ALDH1A1PPARA | |
| SCHEMBL8015012 | 0.77 | PPARD (0.39) | TRPV1TRPV4SRD5A1PPARGPPARA | |
| SCHEMBL4792781 | 0.77 | TRPV1 (0.45) | TRPV1TRPV4SRD5A1DDB1CRBN | |
| SCHEMBL23119102 | 0.76 | TRPV1 (0.38) | TRPV1TRPV4SRD5A1ALDH1A1HPGD | |
| SCHEMBL28110047 | 0.75 | SRD5A1 (0.51) | SRD5A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL1866161 | 0.75 | TRPV1 (0.37) | TRPV1TRPV4SRD5A1ALDH1A1MAPT | |
| SCHEMBL5690949 | 0.75 | TRPV1 (0.37) | TRPV1TRPV4SRD5A1ALDH1A1MAPT | |
| SCHEMBL22758499 | 0.75 | PGR (0.43) | TRPV1TRPV4SRD5A1ALDH1A1MAPT | |
| SCHEMBL24927960 | 0.75 | TRPV1 (0.37) | TRPV1TRPV4SRD5A1KIF11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103688-A | TERT-BUTYL SUBSTITUTED INDAN DERIVATIVES | FIRMENICH SA (CH) | 2000-08-15 | — | — | US | disclosed |
| US-5552379-A | FLORAL, FOR COSMETICS AND HOUSEHOLD ITEMS | FIRMENICH SA (CH) | 1996-09-03 | — | — | US | disclosed |