SCHEMBL7999151

SCHEMBL7999151

Cc1cnc(NCCS)cn1

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 1/20 0.35
CRBN Q96SW2 1/20 0.35
NOTUM Q6P988 1/20 0.35
GRIN2B Q13224 1/20 0.34
HCAR3 P49019 1/20 0.31
CYP1A2 P05177 2/20 0.30
CYP3A4 P08684 2/20 0.30
EDNRA P25101 1/20 0.30
CYP2C19 P33261 1/20 0.30
TSHR P16473 1/20 0.30
CLK4 Q9HAZ1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15382063 0.77 HCAR3 (0.50) NOTUMHCAR3CYP1A2CYP3A4CYP2C19
SCHEMBL2629364 0.74 SIGMAR1 (0.40) CLK4
SCHEMBL20613476 0.72 NMT1 (0.49)
SCHEMBL10293569 0.71 HRH4 (0.44) DDB1CRBNGRIN2B
SCHEMBL15382054 0.69 SMN1; SMN2 (0.59) DDB1CRBNNOTUMHCAR3
SCHEMBL5833413 0.69 CYP1A2 (0.38) CYP1A2CYP3A4CYP2C19TSHRCLK4
SCHEMBL759271 0.69
SCHEMBL5225433 0.67
SCHEMBL82304 0.66
SCHEMBL21017414 0.64 SYK (0.38) DDB1CRBNNOTUMCYP1A2EDNRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109267118-B Electroplating additive for blind hole filling of circuit board and preparation method thereof 深圳市正天伟科技有限公司 2019-12-13 CN claimed
CN-109267118-B Electroplating additive for blind hole filling of circuit board and preparation method thereof 深圳市正天伟科技有限公司 2019-12-13 CN disclosed
CN-109267118-A A kind of route board blind hole filling perforation electroplating additive and preparation method thereof 深圳市正天伟科技有限公司 2019-01-25 CN disclosed
US-6297374-B1 Nitroimino-nitromethylene—azole or-azine heterocyclic compounds, insecticidal compositions containing them, and insecticidal methods of using them NIHON BAYER AGROCHEM K.K. (JP) 2001-10-02 US disclosed
US-6022967-A 1-NITRO-2-CARBOXYVINYL- OR 1-NITRO-2-(DIMETHYLAMINO)VINYL-SUBSTITUTED IMIDAZOLIDINES OR TETRAHYDROPYRIMIDINES NIHON BAYER AGROCHEM K.K. (JP) 2000-02-08 US disclosed
US-5750704-A INSECTICIDES NIHON BAYER AGROCHEM K.K. (JP) 1998-05-12 US disclosed
US-5298507-A Insecticides NIHON BAYER AGROCHEM K.K. (JP) 1994-03-29 US disclosed
US-5204360-A Insecticides NIHON BAYER AGROCHEM K.K. (JP) 1993-04-20 US disclosed
US-5001138-A Insecticides NIHON TOKUSHU NOYAKU SEIZO, K.K. (JP) 1991-03-19 US disclosed
US-4845106-A INSECTICIDES NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1989-07-04 US disclosed
US-4742060-A 2-(NITROIMINO)- OR 2-(NITROMETHYLENE)-IMIDAZOLIDINES AS INSECTICIDES NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) 1988-05-03 US disclosed
EP-0192060-A1 Heterocyclic compounds NIHON BAYER AGROCHEM K.K. (JP) 1986-08-27 EP disclosed