Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34474774 | 0.75 | SLC6A4 (0.48) | — | |
| SCHEMBL12347236 | 0.75 | SLC6A4 (0.48) | — | |
| SCHEMBL12750824 | 0.73 | CA12 (0.36) | CA12CA1CA7CA14NFKB1 | |
| SCHEMBL6118690 | 0.72 | SLC6A4 (0.45) | CA12CA1CA7CA14 | |
| SCHEMBL13494079 | 0.71 | ADH1A (0.41) | CA12CA1CA7CA14NFKB1 | |
| SCHEMBL31210842 | 0.70 | SLC6A4 (0.36) | NFKB1NFKB2RELA | |
| SCHEMBL13331026 | 0.69 | ASGR1 (0.32) | — | |
| SCHEMBL31210582 | 0.68 | NFKB1 (0.33) | CA14NFKB1NFKB2RELA | |
| SCHEMBL4517733 | 0.68 | NFKB1 (0.32) | CA14NFKB1NFKB2RELA | |
| SCHEMBL14157391 | 0.68 | SLC6A2 (0.32) | NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146182-A1 | TRPV4 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-12-03 | — | — | WO | disclosed |