Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 18/20 | 0.61 |
| ▸ | MTOR | P42345 | 17/20 | 0.61 |
| ▸ | PIK3R1 | P27986 | 7/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.41 |
| ▸ | RICTOR | Q6R327 | 4/20 | 0.41 |
| ▸ | RPTOR | Q8N122 | 4/20 | 0.41 |
| ▸ | MAPKAP1 | Q9BPZ7 | 4/20 | 0.41 |
| ▸ | MLST8 | Q9BVC4 | 4/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5886633 | 0.77 | PIK3CA (0.57) | PIK3CAMTORPIK3R1PIK3CBRICTOR | |
| SCHEMBL8008565 | 0.76 | PIK3CA (1.00) | PIK3CAMTORPIK3R1PIK3CBRICTOR | |
| SCHEMBL8003220 | 0.76 | PIK3CA (0.78) | PIK3CAMTORPIK3R1PIK3CBPIK3CG | |
| SCHEMBL8012933 | 0.75 | PIK3CA (0.64) | PIK3CAMTORPIK3R1PIK3CGPIK3CD | |
| SCHEMBL7999531 | 0.74 | PIK3CA (0.72) | PIK3CAMTORPIK3R1PIK3CBRICTOR | |
| SCHEMBL8012871 | 0.74 | PIK3CA (0.79) | PIK3CAMTORPIK3R1PIK3CBPIK3CG | |
| SCHEMBL4018631 | 0.73 | PIK3CA (1.00) | PIK3CAMTORPIK3R1PIK3CBPIK3CG | |
| SCHEMBL19142285 | 0.73 | PIK3CD (0.49) | PIK3CAMTORPIK3R1PIK3CBPIK3CG | |
| SCHEMBL1308989 | 0.72 | PIK3CA (0.61) | PIK3CAMTORPIK3R1PIK3CBPIK3CG | |
| SCHEMBL4018233 | 0.72 | PIK3CA (0.65) | PIK3CAMTORPIK3R1PIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009093981-A1 | TRIAZINE COMPOUNDS AS KINASE INHIBITORS | S BIO PTE LTD (SG) | 2009-07-30 | — | — | WO | disclosed |