⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8348928 | 1.00 | — | — | |
| SCHEMBL8348774 | 1.00 | — | — | |
| SCHEMBL7014418 | 0.93 | ALDH1A1 (0.44) | — | |
| SCHEMBL8348766 | 0.93 | ALDH1A1 (0.44) | — | |
| SCHEMBL11122429 | 0.93 | ALDH1A1 (0.44) | — | |
| SCHEMBL1073890 | 0.93 | ALDH1A1 (0.44) | — | |
| SCHEMBL7638534 | 0.90 | MAPT (0.44) | — | |
| SCHEMBL4515462 | 0.86 | — | — | |
| SCHEMBL8349202 | 0.86 | — | — | |
| SCHEMBL7648990 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6287829-B1 | USING CHIRAL ANCHOR-PROTECTIVE GROUPS | DSM FINE CHEMICAL AUSTRIA NFG GMBH & CO KG (AT) | 2001-09-11 | — | — | US | claimed |
| EP-0335827-B1 | PROCESS FOR THE PREPARATION OF BICYCLO(3.3.0)OCTAN-3-ONE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-07-28 | — | — | EP | claimed |
| EP-0303562-B1 | Process for the preparation of E/Z mixtures of 2-(bicyclo[3.3.0]octan-3-ylidene) acetic-acid derivatives with a major proportion of E or Z isomer | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-01-15 | — | — | EP | claimed |
| WO-1989001470-A1 | PROCESS FOR PRODUCING E/Z MIXTURES OF 2-(BICYCLO[3.3.0]OCTANE-3-YLIDENE) ACETIC ACID DERIVATIVES WITH PREDOMINANT E OR Z MOIETIES | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1989-02-23 | — | — | WO | claimed |
| EP-3810615-B1 | ARGINASE INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2026-01-28 | — | — | EP | disclosed |
| EP-4649143-A1 | ENGINEERED KETOREDUCTASE POLYPEPTIDES | Novartis AG (CH) | 2025-11-19 | — | — | EP | disclosed |
| US-12358887-B2 | IKAROS Zinc Finger Family degraders and uses thereof | GILEAD SCIENCES, INC. (US) | 2025-07-15 | — | — | US | disclosed |
| EP-4464703-A2 | IKAROS ZINC FINGER FAMILY DEGRADERS AND USES THEREOF | Gilead Sciences, Inc. (US) | 2024-11-20 | — | — | EP | disclosed |
| EP-4245756-B1 | IKAROS ZINC FINGER FAMILY DEGRADERS AND USES THEREOF | GILEAD SCIENCES INC (US) | 2024-10-09 | — | — | EP | disclosed |
| WO-2024150146-A1 | ENGINEERED KETOREDUCTASE POLYPEPTIDES | NOVARTIS AG (CH) | 2024-07-18 | — | — | WO | disclosed |
| US-20240150293-A1 | SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | VERNALIS (R&D) LTD (GB) | 2024-05-09 | — | — | US | disclosed |
| US-11897862-B2 | IKAROS zinc finger family degraders and uses thereof | GILEAD SCIENCES, INC. (US) | 2024-02-13 | — | — | US | disclosed |
| EP-0303562-A1 | Process for the preparation of E/Z mixtures of 2-(bicyclo[3.3.0]octan-3-ylidene) acetic-acid derivatives with a major proportion of E or Z isomer | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-02-15 | — | — | EP | disclosed |
| US-4774341-A | CARBOXYLIC ACIDS OR ESTER DERIVATIVES, ANTICOAGULANTS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1988-09-27 | — | — | US | disclosed |
| US-4731458-A | Spiro[bicyclo[3.2.0]heptane-6,2'-oxirane] derivatives | CBD CORPORATION (US) | 1988-03-15 | — | — | US | disclosed |
| US-4644068-A | INTERMEDIATES FOR PG; ANTICOAGULANTS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1987-02-17 | — | — | US | disclosed |
| US-4622410-A | CHEMICAL INTERMEDIATES FOR 6-KETO-PROSTAGLANDINS | ONO PHARMACEUTICAL CO. LTD. (JP) | 1986-11-11 | — | — | US | disclosed |
| EP-0105651-A1 | Bicyclo(3.3.0)octane derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1984-04-18 | — | — | EP | disclosed |
| US-4307112-A | 9-Deoxy-9A-methylene isosteres of PGI2 and process for their preparation | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-12-22 | — | — | US | disclosed |
| EP-0011591-A1 | Prostane derivatives, their production and pharmaceutical compositions containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1980-05-28 | — | — | EP | disclosed |