⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8348928 | 1.00 | — | — | |
| SCHEMBL7999538 | 1.00 | — | — | |
| SCHEMBL7014418 | 0.93 | ALDH1A1 (0.44) | — | |
| SCHEMBL8348766 | 0.93 | ALDH1A1 (0.44) | — | |
| SCHEMBL11122429 | 0.93 | ALDH1A1 (0.44) | — | |
| SCHEMBL1073890 | 0.93 | ALDH1A1 (0.44) | — | |
| SCHEMBL7638534 | 0.90 | MAPT (0.44) | — | |
| SCHEMBL4515462 | 0.86 | — | — | |
| SCHEMBL8349202 | 0.86 | — | — | |
| SCHEMBL7648990 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189747-B2 | Method of treating noninflammatory cartilage damage | WARNER-LAMBERT COMPANY (US) | 2007-03-13 | — | — | US | disclosed |
| US-7189747-B2 | Method of treating noninflammatory cartilage damage | WARNER-LAMBERT COMPANY (US) | 2007-03-13 | — | — | US | disclosed |
| WO-2003063845-A1 | ALPHA 2 DELTA LIGANDS TO TREAT TINNITUS | WARNER-LAMBERT COMPANY LLC (US) | 2003-08-07 | — | — | WO | disclosed |