Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11057810 | 0.81 | KMT2A (0.51) | KMT2AALDH1A1MEN1MAPTRECQL | |
| SCHEMBL3248552 | 0.81 | ALDH1A1 (0.43) | KMT2AALDH1A1MEN1MAPTRECQL | |
| SCHEMBL11111820 | 0.80 | KMT2A (0.50) | KMT2AALDH1A1MEN1MAPTRECQL | |
| SCHEMBL273919 | 0.79 | KMT2A (0.46) | KMT2AALDH1A1MEN1MAPTRECQL | |
| SCHEMBL3244381 | 0.79 | KMT2A (0.46) | KMT2AALDH1A1MEN1MAPTRECQL | |
| SCHEMBL28731129 | 0.79 | KMT2A (0.42) | KMT2AALDH1A1MEN1MAPTRECQL | |
| SCHEMBL13144272 | 0.78 | KMT2A (0.48) | KMT2AALDH1A1MEN1MAPTRECQL | |
| SCHEMBL10972192 | 0.75 | KMT2A (0.40) | KMT2AALDH1A1MEN1MAPTRECQL | |
| SCHEMBL13079880 | 0.73 | KMT2A (0.51) | KMT2AALDH1A1MEN1MAPTRECQL | |
| SCHEMBL12471441 | 0.71 | NPSR1 (0.46) | KMT2AALDH1A1MEN1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000030632-A1 | ARYL AND HETEROARYL COMPOUNDS USEFUL AS FIBROBLAST GROWTH FACTOR ANTAGONISTS | EISAI CO., LTD. (JP) | 2000-06-02 | — | — | WO | claimed |
| WO-2000030632-A1 | ARYL AND HETEROARYL COMPOUNDS USEFUL AS FIBROBLAST GROWTH FACTOR ANTAGONISTS | EISAI CO., LTD. (JP) | 2000-06-02 | — | — | WO | disclosed |
| US-4476208-A | AND PYRYLIUM, THIOPYRYLIUM, BENZOPYRYLIUM OR BENZOTHIOPYRYLIUM RESIDUES | FUJI PHOTO FILM CO., LTD. (JP) | 1984-10-09 | — | — | US | disclosed |