Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.51 |
| ▸ | MEN1 | O00255 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11057810 | 0.82 | KMT2A (0.51) | KMT2AMEN1ALDH1A1MAPTPOLB | |
| SCHEMBL273919 | 0.81 | KMT2A (0.46) | KMT2AMEN1ALDH1A1MAPTPOLB | |
| SCHEMBL13144272 | 0.79 | KMT2A (0.48) | KMT2AMEN1ALDH1A1MAPTPOLB | |
| SCHEMBL11111820 | 0.78 | KMT2A (0.50) | KMT2AMEN1ALDH1A1MAPTPOLB | |
| SCHEMBL12597202 | 0.77 | KMT2A (0.47) | KMT2AMEN1ALDH1A1MAPTPOLB | |
| SCHEMBL9194157 | 0.76 | KMT2A (0.46) | KMT2AMEN1ALDH1A1MAPTPOLB | |
| SCHEMBL9194155 | 0.76 | KMT2A (0.46) | KMT2AMEN1ALDH1A1MAPTPOLB | |
| SCHEMBL3248552 | 0.75 | ALDH1A1 (0.43) | KMT2AMEN1ALDH1A1MAPTPOLB | |
| SCHEMBL18920273 | 0.74 | KMT2A (0.51) | KMT2AMEN1ALDH1A1MAPTPOLB | |
| SCHEMBL16160944 | 0.74 | KMT2A (0.51) | KMT2AMEN1ALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100297215-A1 | COMPOSITIONS AND METHODS FOR PROTECTING CELLS DURING CANCER CHEMOTHERAPY AND RADIOTHERAPY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-11-25 | — | — | US | disclosed |
| US-20090215108-A1 | biochemical conjugate with a dye; biological substance peptide, protein, nucleotide, nucleic acid, carbohydrate, lipid, membrane or cell; detecting optical response upon use of an illumination source; use as luminescent probes valuable reagents for the analysis and separation of molecules and cells | DIWU ZHENJUN | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100297215-A1 | COMPOSITIONS AND METHODS FOR PROTECTING CELLS DURING CANCER CHEMOTHERAPY AND RADIOTHERAPY | UNG, GSTK1, GSTA1 | KMT2A 4554/4885MEN1 3909/4885ALDH1A1 165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.