Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | KMO | O15229 | 3/20 | 0.48 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14997104 | 0.98 | PARP1 (0.56) | PARP1KMOCFTRCA12CA1 | |
| SCHEMBL4274420 | 0.86 | PARP1 (0.72) | PARP1KMOCA12CA1CA2 | |
| SCHEMBL4104709 | 0.85 | PARP1 (0.55) | PARP1ALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL4079910 | 0.85 | PARP1 (0.58) | PARP1KMOCA12CA1CA2 | |
| Phenol SCHEMBL28650467 | 0.79 | PARP1 (0.62) | PARP1KMOCA12CA1CA2 | |
| SCHEMBL2282510 | 0.78 | KMO (0.56) | PARP1KMOCA12CA1CA2 | |
| Aniline SCHEMBL28655458 | 0.78 | PARP1 (0.65) | PARP1KMOCFTRCA12CA1 | |
| SCHEMBL1555687 | 0.76 | DRD3 (0.58) | PARP1TSHR | |
| SCHEMBL3767767 | 0.76 | CHRNB4 (0.40) | PARP1TSHRBACE1 | |
| SCHEMBL23715071 | 0.76 | KMO (0.62) | PARP1KMOCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1011609-A4 | COMPOSITIONS FOR COSMETIC APPLICATIONS | MEDLOGIC GLOBAL CORP (US) | 2000-08-16 | — | — | EP | disclosed |
| EP-1011609-A1 | COMPOSITIONS FOR COSMETIC APPLICATIONS | MedLogic Global Corporation (US) | 2000-06-28 | — | — | EP | disclosed |
| WO-1998050005-A1 | COMPOSITIONS FOR COSMETIC APPLICATIONS | MEDLOGIC GLOBAL CORPORATION (US) | 1998-11-12 | — | — | WO | disclosed |